Scientists have presented the most unequivocal evidence so far that marijuana can ease nausea.
There’s a new study that found that a non-psychoactive compound is proven to prevent nausea in rats.
Drugs that are destined for cancer patients have reduced a few side effects that include vomiting, but nausea has proven itself to be more resistant to the treatment, according to the scientists at the University of Guelph in Ontario, Canada.
As a result, there are a lot of patients who have turned to medical marijuana in order to reduce nausea, but until now, scientists have failed to prove a direct link between the two of them.
Understanding what triggers nausea
Now, this study not only helps in understanding what exactly triggers nausea, but it could also pave the way for more effective therapies.
Doctors and dispensaries can now become more confident and start prescribing medical cannabis as long as they become aware of which strains help ease side effects in patients with cancer.
Nausea occurs when the brain receives signals from various pathways that there’s a toxin in the body.
The brain sends a signal to the body that leads to muscles from the gastrointestinal tract to send its contents towards the mouth in order to remove the toxin.
We knew some of the neurobiology behind nausea, but we had a lot of data that led to a hypothesis that serotonin was triggering it,’ Dr. Linda Parker, a professor of psychology at the University of Guelph, told Daily Mail Online.
Serotonin is a neurotransmitter which helps with better sleeping, eating and digesting.
During the study, rats have been injected with a chemical compound that induces nausea called lithium chloride and a saline placebo.
The scientists studied the brains of rats after that, especially the part of the brain that is responsible for nausea.
They found an increase of serotonin in the rats who have been given the chemical but no in the ones that have received the controlled placebo.
‘We were surprised by the dramatic increase in serotonin followed the effects of nausea,’ said Dr. Parker.
‘It spiked by about 100 percent. We were expecting an increase but not such a dramatic one.’
Cannabis oil can treat nausea
This increase led researchers to prove that the serotonin release was triggering nausea.
To treat this, the team used cannabidiol which is an oil made from the primary compounds of cannabis but without THC which is the psychoactive compound.
The cannabidiol managed to prevent serotonin from rising by activating CB1 receptors in the brain, and this basically opened the door to new therapeutic measure for people who supper from nausea including cancer patients.
Rada attended the courses in the Faculty of Letters, Romanian-English section, and finished the Faculty of Theatre and Television, Theatrical Journalism section, both within the framework of Babeş-Bolyai University of Cluj-Napoca. Up ’til now, she reviewed books, movies, and theatre-plays, enjoying subjects from the cultural niche. Her experience in writing also intersects the IT niche, given the fact that she worked as a content editor for firms that produce software for mobile devices. She is collaborating with online advertising agencies, writing articles for several websites and blogs.