Injectable Bandage Developed by Researchers From Inspired Nanomaterials and Tissue Engineering Laboratory

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Great news for doctors, soldiers and whoever is in need of quickly treating a wound and stop the bleeding! Researchers at the Inspired Nanomaterials and Tissue Engineering Laboratory have developed a bandage that can quickly stop bleeding.

A Gelling Agent We Might Be Familiar With

In the article “Nanoengineered Injectable Hydrogels for Wound Healing Application” which was published in Acta Biomaterialia, the assistant professor in the Department of Biomedical Engineering at Texas A&M University, Dr. Akhilesh K. Gaharwar said that he uses this ‘injectable bandage’ to stop the bleeding and to help wound healing. The substances they used are kappa-carrageenan and nanosilicates, which help to form injectable hydrogels:

“Injectable hydrogels are promising materials for achieving hemostasis in case of internal injuries and bleeding, as these biomaterials can be introduced into a wound site using minimally invasive approaches,” said Dr. Akhilesh K Gaharwar.

He continues presenting the injectable bandage, saying that after it gets to the wound area, it will “promote a natural clotting cascade. In addition, the injectable bandage should initiate wound healing response after achieving hemostasis.”

The thickening gel named kappa-carrageenan is obtained from seaweed, while the hydrogels are similar to jelly, being a network of 3D water-swollen polymer, having the role of simulating human tissue.

The gelatin is obtained by mixing the nanoparticles with kappa-carrageenan, so the gels receive the characteristics of the kappa-carrageenan, clotting the blood in the wound. Moreover, the plasma protein and platelets help with blood absorption in the gel and will then trigger blood clotting.

The Injectable Bandages Heal The Wound

The first author of the paper and graduate student in the lab, Giriraj Lokhande shared the following results:

“Interestingly, we also found that these injectable bandages can show a prolonged release of therapeutics that can be used to heal the wound. The negative surface charge of nanoparticles enabled electrostatic interactions with therapeutics thus resulting in the slow release of therapeutics.”

Their research has been funded by the following institutions: The National Science Foundation’s Chemical, Bioengineering, Environmental and Transport Systems Division, The National Institutes of Health’s National Institute of Biomedical Imaging and Bioengineering.

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Andre Blair s is the lead editor for Advocator.ca. He holds a B.A. in Psychology from the University of Toronto, and a Master of Science in Public Health (M.S.P.H.) from the School of Public Health, Department of Health Administration, at the University of North Carolina at Chapel Hill. Andre specializes in environmental health, but writes on a variety of issues.


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